Imaging plays an important role in both clinical and research environments. This course presents both the basic physics together with the practical technology associated with such methods as X-ray computed tomography (CT), magnetic resonance imaging (MRI), functional MRI (f-MRI) and spectroscopy, ultrasonics (echocardiography, Doppler flow), nuclear medicine (Gallium, PET and SPECT scans) as well as optical methods such as bioluminescence, optical tomography, fluorescent confocal microscopy, two-photon microscopy and atomic force microscopy.