Water & steam systems: (water used as excipient, cleaning   agent, or product diluent) water quality selection criteria; generation,   storage and
 distribution systems; bio-burden control; USP PWS   (purified water systems) and USP WFI (water for injection) systems; engineering   considerations, including specification, design, installation, validation,   operation, testing, and maintenance; common unit operations, including   deionization, reverse osmosis, distillation, ultrafiltration, and ozonation systems;   process considerations, including pretreatment, storage and distribution,   materials of construction, microbial control, pyrogen control, and system   maintenance; FDA requirements; clean-in-place systems; steam generation and distribution systems.